The Ophidian Iris is a Unique Amulet introduced in Season 9 that fully transforms the Hydra skill into a Core damage-dealing ability. It enhances both the number and Diablo 4 Items power of Hydra heads, essentially reworking the classic skill into a powerhouse. With this amulet, Hydra builds no longer rely on cooldowns or filler spells-the summoned hydras themselves become your primary weapons.

Ophidian Iris Stats and Unique Effects

Core Stats

+30.0% Resistance to All Elements
+15.0% Attack Speed
+2 to Primordial Binding
+15.7% Intelligence
+100.0% Pyromancy Damage

Unique Effect

Hydra is now a Core Skill and always summons a 3-headed Hydra whose attacks explode on impact.

For each head above 3 that it would have had, the Hydra instead grows larger and deals 100% increased damage.

What This Means:

Hydra becomes spammable-no more cooldown gating.
Three heads baseline, with the possibility for bonus size and damage from extra heads.
Exploding hydra attacks give massive AoE burst potential.
Makes Hydra Sorcerers fully viable as main DPS builds, especially in high-tier content.

How to Get the Ophidian Iris in Diablo 4 Season 9

You can obtain the Ophidian Iris through three main avenues:

1. Farm-Specific Bosses

Ophidian Iris has a chance to drop from the following three bosses in Season 9:

Echo of Duriel, Maggot King

Location: Gaping Crevasse in southern Gea Kul, Kehjistan.
How to Access Hoard: Collect 3x Shards of Agony by defeating Grigoire or Varshan.
Loot: Duriel's hoard contains multiple Uniques, including Ophidian Iris.

Echo of Andariel, Maiden of Diablo 4 materials for sale Anguish

Location: Hanged Man's Hall, eastern Kehjistan.