Path of Exile 2: Siora, Blade of Path of Exile 2 Currency the Mists Boss Guide

While recruiting the Ezomytes in Path of Exile 2, one of the most dangerous bosses you'll encounter is Siora, Blade of the Mists. Fast, elusive, and armed with devastating lightning and mist abilities, Siora can overwhelm unprepared players. Her battle is tight and claustrophobic, forcing you to constantly move while managing arena mechanics.

This guide will walk you through where to find Siora, her attacks, and the best strategies to defeat her in Path of Exile 2.

Where to Find Siora, Blade of the Mists

You'll encounter Siora during the Recruit the Ezomytes questline in Chapter 1 of the Interludes. After activating all the Megaliths on the Stones of Serle map, Siora spawns in the center of the stone circle.

Key details:

Quest Requirement: Recruit the Ezomytes
Map: Stones of Serle
Prerequisite Boss: Tavakai, the Chieftain
Spawn Location: Central stone circle surrounded by Megaliths

Since Interludes are open-ended, you can challenge Siora any time once the prerequisites are met. If you're struggling at this stage, it may be worthwhile to buy POE2 Items that shore up your resistances and movement tools before entering the arena.
How to Get Atalui's Bloodletting in Path of Exile 2

Unlike many gems in the game that can drop from random sources, Atalui's Bloodletting is drop-restricted. This means you can only acquire it from specific bosses in the endgame.

Sealed Vault Bosses

The gem drops exclusively from Anomaly bosses within the Sealed Vault endgame maps, particularly:

Ytzara, Blood Oracle
Maztli, Flesh-Shaper

Both bosses can be found inside Estazunti's Vault (Sealed Vault Map), which is part of the Atlas endgame mapping system.

Unlocking the Sealed Vault

To enter the Sealed Vault, you must acquire the Idol of Estazunti, a special vault key.

Item Type: Vault Key
Description: Grants access to a Sealed Vault on the Atlas.

The Idol of Estazunti is not guaranteed. Instead, it randomly drops from enemies in maps surrounding the Sealed Vault region on the Atlas, making farming necessary. Given its RNG nature, you may need to grind extensively before gaining consistent access to the Vault and buy POE 2 Exalted Orbs its bosses.